Dr. Gilles R. G. Monif’s book “The Prevention and Therapy of Crohn’s Disease” praises the contributions that Professor Karel Hruska’s has made to understanding the events that combine to produce Crohn’s disease. Professor Hruska was the first investigator to identify the significant presence of a mycobacterium, Mycobacterium avium subspecies paratuberculosis (MAP) in infant formula globally. He documented that MAP had to be present in milking herds before Crohn’s disease appeared in the general population.
Doctor Monif pays homage to Professor Hruska and the price he paid personally for bringing unwanted facts into evidence by naming his explanation of the pathogenesis of Crohn’s disease after Professor Hruska. The Hruska Postulate explained how Crohn’s disease started as infectious and became immune-mediated. This revolutionary theory is changing Crohn’s disease research and its clinical management.
Doctor Monif’s Hruska Postulate has changed our view of Crohn’s disease, its genesis, prevention, and therapy. His work stands open a portal into understanding other so-called autoimmune diseases.